Recent scientific evidence proves that there is a verifiable state of conscious identity, distinct from the ego, associated with hemispheric synchronisation and whole-brain activation [1]. This distinct sense of self coincides with the experience of being feeling-awareness itself, in contrast to identifying with the body and mind [2]. The native qualities of feeling-awareness itself are experienced at the subject-pole of attention in moments of presence, in the form of wisdom, compassion, integrity, joy, love, creativity, and peace [3]. Thus the qualities traditionally ascribed to the soul have an accessible psychological location, associated with a distinct sense of self, with a detectable neurological signature [4]. This combined evidence, upon which the SQ paradigm is based, constitutes a neuro-psycho-spiritual synthesis, representing the science of the soul.